Science
Longevity Science Map
Explore the biology of longevity. The biological systems and mechanisms that shape human aging, mapped to the evidence behind them.
How the map works
- 10 science themes
The major biological systems and mechanisms LONGEFI tracks.
- Evidence records
Structured findings extracted from a development, with provenance.
- Source documents
The original publications and filings every record traces back to.
Explore the 10 science themes
- 01Cellular reprogrammingPartially resetting a cell's age without erasing what the cell is.
- 02SenolyticsClearing worn-out cells that stop dividing but keep signalling inflammation.
- 03Gene therapyEditing or adding genetic instructions directly inside the body.
- 04EpigeneticsThe chemical marks that decide which genes a cell actually uses.
- 05Stem cellsReplacing or reactivating the cells that rebuild tissue.
- 06mTORA cellular growth switch that, when dialled down, extends life in animals.
- 07NAD+A molecule cells need for energy and repair that declines with age.
- 08ImmunologyWhy the immune system weakens and inflames as we age.
- 09Metabolic healthHow the body handles fuel — the earliest measurable part of aging.
- 10AI drug discoveryUsing models to find candidate drugs faster than lab screening allows.