Science
Gene therapy
Editing or adding genetic instructions directly inside the body.
What it is
In vivo editing has moved from concept to multi-year durable human data. For longevity, the important variable is not the first indication but whether delivery and safety generalise to preventive use.
Key mechanisms and technologies
- In vivo CRISPR
- Base editing
- Lipid nanoparticle delivery
- Redosing strategies
Published LONGEFI developments are listed chronologically in the News archive.