Science · Developing

mTOR

mTOR inhibition is the most reproducible lifespan intervention in model organisms. Human translation has repeatedly failed on clinical endpoints, making selectivity and endpoint choice the decisive variables.

Latest research

mTORClinicalTrials.gov · 2 Aug 2026

Signal45·Moderate

Selective mTOR inhibitor begins Phase 2 in adults over 65

A selective TORC1 inhibitor entered Phase 2 testing for respiratory infection incidence in older adults. The design follows a previous programme in…

EvidenceEarlyMarket relevanceLow4 min read