Science
Epigenetics
The chemical marks that decide which genes a cell actually uses.
What it is
Epigenetic patterns drift with age and can be measured as biological clocks. Whether clock changes cause aging or merely track it remains the central open question, and it determines how much weight to give clock-based endpoints.
Key mechanisms and technologies
- DNA methylation clocks
- Transcriptomic age
- Chromatin remodelling
- Clock-based trial endpoints
Published LONGEFI developments are listed chronologically in the News archive.