LONGEFI
Company · Private

Tornado Therapeutics

Developing selective TORC1 inhibitors intended to improve immune function in older adults.

EvidenceEarlyHistory of endpoint misses
Listing
Private
Ticker
Headquarters
Boston, US
Founded
2020
Technology
mTOR inhibition / immune aging
Category
Market cap
Private

Longevity thesis

Selective mTOR inhibition can capture rapamycin's benefits without broad immunosuppression.

Pipeline

ProgrammeStageFocus
TOR-114Phase 2Respiratory infection in older adults

Recent developments

  • 25 Jul 2026Started a Phase 2 in adults over 65.

Scientific evidence

EvidenceEarly

Previous efforts in this mechanism failed a pivotal endpoint; selectivity is the open question.

LONGEFI analysis

Historically the most disappointing longevity mechanism in the clinic. LONGEFI applies an elevated evidence bar here.

Analysis is research commentary. It is not investment advice or a recommendation.